Statistics in Medicine

Table of Contents

Volume 19 Issue 4 (29 February 2000)




  • Author: Helmut Schäfer, Mitchell H. Gail, Patrick Royston
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<421::AID-SIM346>3.0.CO;2-Y (p 421-421)

Research Articles

Prognosis – what does the clinician associate with this notion?

  • Author: Jürgen Windeler
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<425::AID-SIM347>3.0.CO;2-J (p 425-430)

Prevalence‐free utility‐respecting summary indices of diagnostic power do not exist

  • Author: Jørgen Hilden
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<431::AID-SIM348>3.0.CO;2-R (p 431-440)

Sample size considerations for the evaluation of prognostic factors in survival analysis

  • Author: Claudia Schmoor, Willi Sauerbrei, Martin Schumacher
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<441::AID-SIM349>3.0.CO;2-N (p 441-452)

What do we mean by validating a prognostic model?

  • Author: Douglas G. Altman, Patrick Royston
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<453::AID-SIM350>3.0.CO;2-5 (p 453-473)

Tree stability diagnostics and some remedies for instability

  • Author: Felix Dannegger
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<475::AID-SIM351>3.0.CO;2-V (p 475-491)

Regional confidence bands for ROC curves

  • Author: Katrin Jensen, Hans‐Helge Müller, Helmut Schäfer
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<493::AID-SIM352>3.0.CO;2-W (p 493-509)

Comparison of diagnostic markers with repeated measurements: a non‐parametric ROC curve approach

  • Author: Birol Emir, Sam Wieand, Sin‐Ho Jung, Zhiliang Ying
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<511::AID-SIM353>3.0.CO;2-3 (p 511-523)

Statistical methods for the evaluation of diagnostic measurements concerning paired organs

  • Author: P. Martus
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<525::AID-SIM354>3.0.CO;2-O (p 525-540)

On the misuses of artificial neural networks for prognostic and diagnostic classification in oncology

  • Author: Guido Schwarzer, Werner Vach, Martin Schumacher
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<541::AID-SIM355>3.0.CO;2-V (p 541-561)

Choice of conditional models in bivariate survival

  • Author: Robin Henderson, Helen Prince
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<563::AID-SIM356>3.0.CO;2-K (p 563-574)

Methods of ordinal classification applied to medical scoring systems

  • Author: Uwe Feldmann, Ingo Steudel
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<575::AID-SIM357>3.0.CO;2-A (p 575-586)

Multi‐state models for bleeding episodes and mortality in liver cirrhosis

  • Author: Per Kragh Andersen, Sille Esbjerg, Thorkild I. A. Sørensen
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<587::AID-SIM358>3.0.CO;2-0 (p 587-599)

Identifying and modelling prognostic factors with censored data

  • Author: Artur Klinger, Felix Dannegger, Kurt Ulm
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<601::AID-SIM359>3.0.CO;2-K (p 601-615)

Statistical models for longitudinal biomarkers of disease onset

  • Author: Elizabeth H. Slate, Bruce W. Turnbull
  • Pub Online: Feb 23, 2000
  • DOI: 10.1002/(SICI)1097-0258(20000229)19:4<617::AID-SIM360>3.0.CO;2-R (p 617-637)

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