## Marginal information for expectation parameters

### Abstract

The authors consider a special case of inference in the presence of nuisance parameters. They show that when the orthogonalized score function is a function of a statistic S, no Fisher information for the interest parameter is lost by using the marginal distribution of S rather than the full distribution of the observations. Therefore, no information for the interest parameter is recovered by conditioning on an ancillary statistic, and information will be lost by conditioning on an approximate ancillary statistic. This is the case for regular multivariate exponential families when the interest parameter is a subvector of the expectation parameter and the statistic is the maximum likelihood estimate of the interest parameter. Several examples are considered, including the 2 × 2 table.

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