5th Annual Adaptive Designs in Clinical Trials


The expert speakers at the 8th annual Adaptive Designs in Clinical Trials – the only conference in Europe to focus specifically on adaptive designs – are widely regarded as industry leaders. Through their first-hand accounts and in-depth case studies you will learn how to quickly and accurately implement an adaptive design clinical trial for your drug development from initial processes in managing trials to choosing the right time to implement change.

Key topics include:
• The motivation, promise, and success of Bayesian adaptive trial design
• An adaptive design to explore prevention therapies for Alzheimer's Disease
• Controlling the weighted sum of Type I and Type II errors, and implications for the design and analysis of adaptive designs
• From preclinical studies to adaptive designs – a path to the future
• Bayesian Variable Selection (BVS) approach for dose-response modelling
• Adaptive sample size and modification in clinical trials: start small then ask for more?
• Adaptive trials in pre-clinical discovery
• Paediatric adaptation: early (stage) we practice, later perhaps we practice less
• Designing multi-arm multi-stage clinical trials
• Exploratory dose finding in malaria

Speakers include:
Andy Kenwright, Project Statistician, Roche Products
Emmanuel Pham, Senior Director Global R&D Statistics, Ipsen
Vladimir Anisimov, Senior Strategic Biostatistics Director, Quintiles
Christopher Jennison, Professor of Statistics, University of Bath
Frank Fleischer, Teamleader Clinical Biostatistics, Boehringer-Ingelheim
Micheal Krams, VP – Head of Neurology Franchise, Johnson & Johnson
Thomas Jaki, Researcher, Department of Mathematics and Statistics, Lancaster University
Martin Simán, Director, AstraZeneca
Jouni Kerman, Statistical Methodologist, Novartis
Alun Bedding, Director, Biostatistics and Programming Development Partners, GlazoSmithKline
and more . . .

For the in-depth programme, full speaker line-up and to register visit http://www.smi-online.co.uk/goto/adaptivedesigns35.asp. Alternatively, call Cem Tuna on +44 (0)20 7827 6736 or email him on ctuna@smi-online.co.uk.  

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