Genetic Epidemiology

Early View Articles

Research Articles

Imputed gene associations identify replicable trans‐acting genes enriched in transcription pathways and complex traits

  • Author: Heather E. Wheeler, Sally Ploch, Alvaro N. Barbeira, Rodrigo Bonazzola, Angela Andaleon, Alireza Fotuhi Sishpirani, Ashis Saha, Alexis Battle, Sushmita Roy, Hae Kyung Im
  • Pub Online: Apr 04, 2019
  • DOI: 10.1002/gepi.22205 (p )

Brief Reports

Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective

  • Author: Jue‐Sheng Ong, Stuart MacGregor
  • Pub Online: May 02, 2019
  • DOI: 10.1002/gepi.22207 (p )

Research Articles

Rare variant association testing for multicategory phenotype

  • Author: Ozvan Bocher, Gaëlle Marenne, Aude Saint Pierre, Thomas E. Ludwig, Stéphanie Guey, Elisabeth Tournier‐Lasserve, Hervé Perdry, Emmanuelle Génin
  • Pub Online: May 13, 2019
  • DOI: 10.1002/gepi.22210 (p )

Exome chip‐driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups

  • Author: Sohee Han, Mi Yeong Hwang, Kyungheon Yoon, Yun Kyoung Kim, Young‐Jin Kim, Bong‐Jo Kim, Sanghoon Moon
  • Pub Online: May 13, 2019
  • DOI: 10.1002/gepi.22208 (p )

Integrative analysis of Dupuytren's disease identifies novel risk locus and reveals a shared genetic etiology with BMI

  • Author: Megan Major, Malika K. Freund, Kathryn S. Burch, Nicholas Mancuso, Michael Ng, Dominic Furniss, Bogdan Pasaniuc, Roel A. Ophoff
  • Pub Online: May 13, 2019
  • DOI: 10.1002/gepi.22209 (p )

Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participants

  • Author: Burcu F. Darst, Qiongshi Lu, Sterling C. Johnson, Corinne D. Engelman
  • Pub Online: May 18, 2019
  • DOI: 10.1002/gepi.22211 (p )

A comparison of two workflows for regulome and transcriptome‐based prioritization of genetic variants associated with myocardial mass

  • Author: Elisabetta Manduchi, Daiane Hemerich, Jessica Setten, Vinicius Tragante, Magdalena Harakalova, Jiayi Pei, Scott M. Williams, Pim Harst, Folkert W. Asselbergs, Jason H. Moore
  • Pub Online: May 30, 2019
  • DOI: 10.1002/gepi.22215 (p )

A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals

  • Author: Jenna C. Carlson, Deepti Anand, Azeez Butali, Carmen J. Buxo, Kaare Christensen, Frederic Deleyiannis, Jacqueline T. Hecht, Lina M. Moreno, Ieda M. Orioli, Carmencita Padilla, John R. Shaffer, Alexandre R. Vieira, George L. Wehby, Seth M. Weinberg, Jeffrey C. Murray, Terri H. Beaty, Irfan Saadi, Salil A. Lachke, Mary L. Marazita, Eleanor Feingold, Elizabeth J. Leslie
  • Pub Online: Jun 06, 2019
  • DOI: 10.1002/gepi.22214 (p )

Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study

  • Author: Stephanie J. Loomis, Adrienne Tin, Josef Coresh, Eric Boerwinkle, James S. Pankow, Anna Köttgen, Elizabeth Selvin, Priya Duggal
  • Pub Online: Jun 19, 2019
  • DOI: 10.1002/gepi.22243 (p )

PAMAM: Power analysis in multiancestry admixture mapping

  • Author: Tesfaye B. Mersha, Siqi Chen, Sudhir Ghandikota, Yadu Gautam
  • Pub Online: Jun 26, 2019
  • DOI: 10.1002/gepi.22216 (p )

Using GWAS top hits to inform priors in Bayesian fine‐mapping association studies

  • Author: Kevin Walters, Angela Cox, Hannuun Yaacob
  • Pub Online: Jul 09, 2019
  • DOI: 10.1002/gepi.22212 (p )

Bayesian variable selection using partially observed categorical prior information in fine‐mapping association studies

  • Author: Abdulaziz A. Alenazi, Angela Cox, Miguel Juarez, Wei‐Yu Lin, Kevin Walters
  • Pub Online: Jul 12, 2019
  • DOI: 10.1002/gepi.22213 (p )

Heritability estimation of dichotomous phenotypes using a liability threshold model on ascertained family‐based samples

  • Author: Wonji Kim, Soo Heon Kwak, Sungho Won
  • Pub Online: Jul 12, 2019
  • DOI: 10.1002/gepi.22244 (p )

Fine‐Mapping Additive and Dominant SNP Effects Using Group‐LASSO and Fractional Resample Model Averaging

  • Author: Jeremy Sabourin, Andrew B. Nobel, William Valdar
  • Pub Online: Nov 21, 2014
  • DOI: 10.1002/gepi.21869 (p )

Population Genetic Simulations of Complex Phenotypes with Implications for Rare Variant Association Tests

  • Author: Lawrence H. Uricchio, Raul Torres, John S. Witte, Ryan D. Hernandez
  • Pub Online: Nov 21, 2014
  • DOI: 10.1002/gepi.21866 (p )
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