Statistics in Medicine

Early View Articles

Research Articles

Adaptive trial designs in diagnostic accuracy research

  • Author: Antonia Zapf, Maria Stark, Oke Gerke, Christoph Ehret, Norbert Benda, Patrick Bossuyt, Jon Deeks, Johannes Reitsma, Todd Alonzo, Tim Friede
  • Pub Online: Nov 27, 2019
  • DOI: 10.1002/sim.8430 (p )

Generalized multiple contrast tests in dose‐response studies

  • Author: Shiyang Ma, Michael P. McDermott
  • Pub Online: Dec 03, 2019
  • DOI: 10.1002/sim.8444 (p )

An empirical comparison of two novel transformation models

  • Author: Yuqi Tian, Torsten Hothorn, Chun Li, Frank E. Harrell, Bryan E. Shepherd
  • Pub Online: Dec 06, 2019
  • DOI: 10.1002/sim.8425 (p )

A surrogate ℓ0 sparse Cox's regression with applications to sparse high‐dimensional massive sample size time‐to‐event data

  • Author: Eric S. Kawaguchi, Marc A. Suchard, Zhenqiu Liu, Gang Li
  • Pub Online: Dec 09, 2019
  • DOI: 10.1002/sim.8438 (p )

Dynamic predictive probabilities to monitor rapid cystic fibrosis disease progression

  • Author: Rhonda D. Szczesniak, Weiji Su, Cole Brokamp, Ruth H. Keogh, John P. Pestian, Michael Seid, Peter J. Diggle, John P. Clancy
  • Pub Online: Dec 09, 2019
  • DOI: 10.1002/sim.8443 (p )

Extending the mixed‐effects model to consider within‐subject variance for Ecological Momentary Assessment data

  • Author: Rachel Nordgren, Donald Hedeker, Genevieve Dunton, Chih‐Hsiang Yang
  • Pub Online: Dec 17, 2019
  • DOI: 10.1002/sim.8429 (p )

The emerging landscape of health research based on biobanks linked to electronic health records: Existing resources, statistical challenges, and potential opportunities

  • Author: Lauren J. Beesley, Maxwell Salvatore, Lars G. Fritsche, Anita Pandit, Arvind Rao, Chad Brummett, Cristen J. Willer, Bhramar Mukherjee, Lynda D. Lisabeth
  • Pub Online: Dec 20, 2019
  • DOI: 10.1002/sim.8445 (p )

Semiparametric Bayesian variable selection for gene‐environment interactions

  • Author: Jie Ren, Fei Zhou, Xiaoxi Li, Qi Chen, Hongmei Zhang, Shuangge Ma, Yu Jiang, Cen Wu
  • Pub Online: Dec 21, 2019
  • DOI: 10.1002/sim.8434 (p )

Modeling the overdetection of screen‐identified cancers in population‐based cancer screening with the Coxian phase‐type Markov process

  • Author: Hsiu‐Hsi Chen, Amy Ming‐Fang Yen
  • Pub Online: Dec 19, 2019
  • DOI: 10.1002/sim.8437 (p )

A flexible copula‐based approach for the analysis of secondary phenotypes in ascertained samples

  • Author: Karim Oualkacha, Celia Greenwood, Geneviève Lefebvre, Fodé Tounkara
  • Pub Online: Dec 23, 2019
  • DOI: 10.1002/sim.8416 (p )

Mendelian randomization using semiparametric linear transformation models

  • Author: Yen‐Tsung Huang
  • Pub Online: Dec 27, 2019
  • DOI: 10.1002/sim.8449 (p )

Featured Articles

Novel methods for the analysis of stepped wedge cluster randomized trials

  • Author: Lee Kennedy‐Shaffer, Victor Gruttola, Marc Lipsitch
  • Pub Online: Dec 26, 2019
  • DOI: 10.1002/sim.8451 (p )

Research Articles

An exact test with high power and robustness to unmeasured confounding effects

  • Author: Michal Shauly‐Aharonov
  • Pub Online: Jan 07, 2020
  • DOI: 10.1002/sim.8460 (p )

An evaluation of statistical approaches to postmarketing surveillance

  • Author: Yuxin Ding, Marianthi Markatou, Robert Ball
  • Pub Online: Jan 08, 2020
  • DOI: 10.1002/sim.8447 (p )

A note on the bias of standard errors when orthogonality of mean and variance parameters is not satisfied in the mixed model for repeated measures analysis

  • Author: Kazushi Maruo, Ryota Ishii, Yusuke Yamaguchi, Masaaki Doi, Masahiko Gosho
  • Pub Online: Jan 09, 2020
  • DOI: 10.1002/sim.8474 (p )
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