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The latest content from StatisticsViews.http://www.statisticsviews.comToward resistance‐compromised DHFR inhibitors part 1: Combined structure/ligand‐based virtual screenings and ADME‐Tox profiling
http://www.statisticsviews.com/details/journalArticle/9627741/Toward-resistancecompromised-DHFR-inhibitors-part-1-Combined-structureligandbase.html
The front‐line antimalarial drugs, for example, chloroquine, mefloquine, sulfadoxine, pyrimethamine, atovaquone, and artemether,
are often failing because of the worldwide spread of drug‐resistant parasites. There has been significant recent interest
in virtual screening to drive innovative drug discovery and to combat resistance efforts for a wide range of diseases. In
fact, virtual screening has become the “gold standard” for major...]]>2016-07-27T06:56:24ZA heuristic and parallel simulated annealing algorithm for variable selection in near‐infrared spectroscopy analysis
http://www.statisticsviews.com/details/journalArticle/9627751/A-heuristic-and-parallel-simulated-annealing-algorithm-for-variable-selection-in.html
A new heuristic and parallel simulated annealing algorithm was proposed for variable selection in near‐infrared spectroscopy
analysis. The algorithm employs a parallel mechanism to enhance the search efficiency, a heuristic mechanism to generate high‐quality
candidate solutions, and the concept of Metropolis criterion to estimate accuracy of the candidate solutions. Several near‐infrared
datasets have been evaluated under the proposed new...]]>2016-07-27T06:40:35ZGlobal solutions for the incompressible rotating stably stratified fluids
http://www.statisticsviews.com/details/journalArticle/9628911/Global-solutions-for-the-incompressible-rotating-stably-stratified-fluids.html
We consider the initial value problem of the 3D incompressible Boussinesq equations for rotating stratified fluids. We establish
the dispersive and the Strichartz estimates for the linear propagator associated with both the rotation and the stable stratification.
As an application, we give a simple proof of a unique existence of global in time solutions to our system using just a contraction
mapping principle.]]>2016-07-27T01:30:36ZPerturbation of the CR fractional Yamabe problem
http://www.statisticsviews.com/details/journalArticle/9628901/Perturbation-of-the-CR-fractional-Yamabe-problem.html
In this note, we first prove the non‐degeneracy property of extremals for the optimal Hardy–Littlewood–Sobolev inequality
on the Heisenberg group, as an application, a perturbation result for the CR fractional Yamabe problem is obtained, this generalizes
a classical result of Malchiodi and Uguzzoni .]]>2016-07-27T01:30:03ZA direct approach to quaternionic manifolds
http://www.statisticsviews.com/details/journalArticle/9628921/A-direct-approach-to-quaternionic-manifolds.html
The recent definition of slice regular function of several quaternionic variables suggests a new notion of quaternionic manifold.
We give the definition of quaternionic regular manifold, as a space locally modeled on
H
n
, in a slice regular sense. We exhibit some significant classes of examples, including manifolds which carry a quaternionic
affine...]]>2016-07-27T01:29:27ZConvergence for a family of neural network operators in Orlicz spaces
http://www.statisticsviews.com/details/journalArticle/9628891/Convergence-for-a-family-of-neural-network-operators-in-Orlicz-spaces.html
In this paper, we develop the theory for a family of neural network (NN) operators of the Kantorovich type, in the general
setting of Orlicz spaces. In particular, a modular convergence theorem is established. In this way, we study the above family
of operators in many instances of useful spaces by a unique general approach. The above NN operators provide a constructive
approximation process, in which the coefficients, the weights, and...]]>2016-07-27T01:28:33ZThe progressive censoring signature of coherent systems
http://www.statisticsviews.com/details/journalArticle/9628951/The-progressive-censoring-signature-of-coherent-systems.html
The distribution of a coherent system based on IID components can be written as a mixture of the distributions of progressively
Type‐II censored order statistics. The coefficients in that representation are called the progressive censoring signature
(PC‐signature) of the system. In this paper, we explore the basic properties and potential applications of these mixture representations.
We show that they can be used to study the associated...]]>2016-07-27T00:30:36ZModeling Wear in Cylinder Liners
http://www.statisticsviews.com/details/journalArticle/9628961/Modeling-Wear-in-Cylinder-Liners.html
We present and discuss a stochastic model describing the wear process of cylinder liners in a marine diesel engine. The model
is based on a stochastic differential equation, and Bayesian inference is illustrated. Corrosive action and measurement error,
both quite negligible, are modeled with a Wiener process whereas a jump process is used to describe the contribution of soot
particles to the wear process. The model can be used to forecast...]]>2016-07-26T23:10:30ZDynamic models for estimating the effect of HAART on CD4 in observational studies: Application to the Aquitaine Cohort and the Swiss HIV Cohort Study
http://www.statisticsviews.com/details/journalArticle/9628941/Dynamic-models-for-estimating-the-effect-of-HAART-on-CD4-in-observational-studie.html
Summary
Highly active antiretroviral therapy (HAART) has proved efficient in increasing CD4 counts in many randomized clinical trials.
Because randomized trials have some limitations (e.g., short duration, highly selected subjects), it is interesting to assess
the effect of treatments using observational studies. This is challenging because treatment is started preferentially in subjects
with severe conditions....]]>2016-07-26T21:25:42ZChaos and complexity in mine grade distribution series detected by nonlinear approaches
http://www.statisticsviews.com/details/journalArticle/9623871/Chaos-and-complexity-in-mine-grade-distribution-series-detected-by-nonlinear-app.html
In this article, the underlying dynamics of treating grade distribution is interpreted as a chaotic system instead of a stochastic
system for a better understanding. Here, we study the behavior of grade distribution spatial series acquired at the Chadormalu
mine in Bafgh city of Iran to distinguish the possible existence of low‐dimensional deterministic chaos. This work applies
a variety of nonlinear techniques for detecting the chaotic...]]>2016-07-26T09:42:11Z